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Author information Copyright and License information Disclaimer. Hemodynamic events in a prospective randomised trial of propranolol versus placebo in the prevention of a first variceal hemorrhage. Relationship between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis. All searches will be performed using the electronic search strategies described in Appendix 1. Barjesh Chander Sharma, Email: Annals of Internal Medicine ;

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Trials wonspirs which the allocation sequence generation or allocation concealment was inadequate ie, using allocation systems based on dates, names, admittance numbers, or similar will be excluded from the present review.

Gastroenterology ; 99 5: Maintenance of hemodynamic response to treatment for portal hypertension and influence on complications of cirrhosis. To achieve the maximum statistical power in the sensitivity analyses, all trials will be combined.

winspirs 5.0

Types of outcome measures Primary outcome measure 1 Rebleeding diagnosed by endoscopy or identification of haematemesis, melena, or gastric aspirate containing blood. Hemodynamic events in a prospective randomised trial of propranolol versus placebo in the prevention of a first variceal hemorrhage.

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What’s new Date Event Description 3 May Amended The editorial group responsible for this previously published document have withdrawn it from publication. Your PC will remain clean, speedy and able to take on new tasks. All authors approved of the final version of the protocol. Patients with portal hypertension who have bled from oesophageal varices have a high risk of rebleeding.

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Methods Criteria for considering studies for this review Types of studies We will include randomised clinical trials irrespective of blinding, publication status, or language.

Author information Copyright and License information Disclaimer. All searches will be performed using the electronic search strategies described in Appendix 1. Winsirs not showing reduction in HVPG of this degree are called nonresponders. Furthermore, a number of endoscopic treatments including sclerotherapy and banding ligation are increasingly used to wiinspirs rebleeding.

winspirs 5.0

50. We will include randomised clinical trials irrespective of blinding, publication status, or language. Patients with oesophageal varices and a history of upper gastrointestinal bleeding, likely to be variceal in origin will be included irrespective of the aetiology of portal hypertension, ie, cirrhosis or other liver disease. Relationship between portal pressure response to pharmacotherapy and risk of recurrent variceal haemorrhage in patients with cirrhosis.

Details about the application winsprs want to remove, by pressing the Properties button. Gastroenterology Clinics of North America ; One author BCS will perform the searches. Journal of Hepatology ; Cochrane Handbook for Systematic Reviews of Interventions 4.

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Additional trials will be identified through scanning of reference lists in relevant papers and conference proceedings and through correspondence with experts and pharmaceutical companies. National Center for Biotechnology InformationU.

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The question has been assessed in a number of trials, but the results are equivocal. Annals of Internal Medicine ; Hepatology ; 8 2: Here are some detailed instructions about winspirz to do this: Types of interventions We will perform the following comparisons: Baillieres Clinical Gastroenterology ; A drug therapy for the prevention of variceal hemorrhage.

Primary authors of the included trials will be contacted for additional information if 5.00 measures are not included in the published trial reports.

Primary outcome measure 1 Rebleeding diagnosed by endoscopy or identification of haematemesis, melena, or gastric aspirate containing blood. The treatment of portal hypertension: Blinding Adequate an identical placebo was used to achieve blinding.